Simple Bone Cyst
1. Definition
Unicameral cavity filled with clear or bloody fluid and limited by a membrane of variable thickness, with vascularized connective tissue showing osteoclastic giant cells and some areas with recent or old hemorrhage or fissures with cholesterol-rich content (OMS)
Simple Bone Cyst
2. Incidence
In our musculoskeletal tumor clinic, we observed a predominance of cases in the age group between 5 and 15 years, with a slight predominance of cases in males, and the majority involving the proximal metaphyseal region of the humerus and femur. The vast majority are referred due to an episode of fracture caused by trauma at the site of the injury or as an x-ray finding during an eventual x-ray taken due to some trauma suffered by the patient.
3. Etiology
Although its recognition from a radiographic point of view is simple, its etiology is still unknown. Our hypothesis is that this is a vascular phenomenon. In several cases, when they are treated with infiltration, we inject contrast and observe the existence of vascular fistulas associated with the persistence of the lesion, figures 1 to 3 and video 1.
4. Clinical Assessment
Most patients present asymptomatically, and fractures are often the reason for their first consultation with an orthopedist. Some patients report sporadic episodes of pain or functional limitation before the presence of a bone cyst is diagnosed. Figure 4 illustrates its characteristics.
5. Radiographic Characteristics
The Simple Bone Cyst presents as a radio-transparent lesion in the metaphyseal region of long bones, centrally located, mainly in the proximal region of the humerus and femur and close to the epiphyseal line. They are well-defined lesions, with sclerotic edges, rarely crossing the limits of the cortex or the limits of the bone, expanding, thinning the cortex, but almost never breaking it. In some cases, the “fallen fragment” sign can be observed, which represents fragments of the cortical wall loose within the cyst.
6. Differential diagnosis
The main differential diagnoses are aneurysmal bone cyst, cortical fibrous defect / non-ossifying fibroma, eosinophilic granuloma, juxta-articular bone cyst, fibrous dysplasia, among others, figures 5 to 11.
7. Treatment
COS treatment depends on its location and size, in the vast majority of cases it can be conservative and non-operative. In general, treatment for the upper limb is less surgical and more conservative, whereas treatment for the lower limb tends to be more surgical, in an attempt to avoid a fracture. The classic treatment consists of infiltrations with corticosteroids (depomedrol), observing whether or not bone content is formed inside. If there is an imminent fracture in a load-bearing bone, we should seriously consider the possibility of intralesional treatment by filling the cavity with an autologous graft, preferably, figures 12 to 34.
Author: Prof. Dr. Pedro Péricles Ribeiro Baptista
Orthopedic Oncosurgery at the Dr. Arnaldo Vieira de Carvalho Cancer Institute
Office : Rua General Jardim, 846 – Cj 41 – Cep: 01223-010 Higienópolis São Paulo – SP
Phone: +55 11 3231-4638 Cell:+55 11 99863-5577 Email: drpprb@gmail.com